Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506798 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8507286 | 0.84 | RARB (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8507282 | 0.84 | RARB (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8504618 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8506479 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8506275 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8506477 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8504614 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8507486 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8506276 | 0.84 | MAPT (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563146-B1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| EP-0930301-A1 | 2-Fluoropyridine, process for producing it and its use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5630962-A | 2-Fluoropyridines, their preparation and their use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0563146-A1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011241-A1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-09 | — | — | WO | disclosed |