Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507286 | 1.00 | RARB (0.39) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL8903759 | 0.93 | RARB (0.35) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL8903747 | 0.93 | RARB (0.35) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL8506802 | 0.84 | KDM4E (0.45) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL8506798 | 0.84 | KDM4E (0.45) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9618457 | 0.84 | KDM4E (0.49) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9618458 | 0.84 | KDM4E (0.49) | RARBKDM4EALDH1A1HPGDHTT | |
| SCHEMBL8902970 | 0.83 | CNR2 (0.38) | HTTSMN1; SMN2 | |
| SCHEMBL9505837 | 0.83 | RARB (0.41) | RARBS1PR5FAAHS1PR1S1PR3 | |
| SCHEMBL8902962 | 0.83 | CNR2 (0.38) | HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563146-B1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1999-10-06 | — | — | EP | claimed |
| US-5630962-A | 2-Fluoropyridines, their preparation and their use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |