Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7637618 | 0.98 | CYP1A2 (0.49) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Phosphoric Acid SCHEMBL8506894 | 0.92 | CYP1A2 (0.44) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Phosphoric Acid SCHEMBL17529946 | 0.92 | CYP1A2 (0.44) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Phosphoric Acid SCHEMBL28146726 | 0.91 | CYP1A2 (0.43) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Phosphoric Acid SCHEMBL8506893 | 0.88 | CYP1A2 (0.46) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| SCHEMBL1221710 | 0.87 | KDM4E (0.50) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Benzene SCHEMBL29130108 | 0.87 | KDM4E (0.54) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Hydrogen Sulfide SCHEMBL5998579 | 0.87 | KDM4E (0.54) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| SCHEMBL81238 | 0.87 | KDM4E (0.54) | CYP1A2KDM4EALDH1A1TDP1BCHE | |
| Diethyl Hydrogen Phosphate SCHEMBL4623337 | 0.86 | KCNH2 (0.44) | CYP1A2KDM4EALDH1A1TDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5868943-A | Waste treatment process for the disposal of dichlorodifluoromethane by conversion into polytetrafluoroethylene | DONNELLY JR JOSEPH L (US) | 1999-02-09 | — | — | US | disclosed |
| US-4552942-A | Silanes and compositions prepared therefrom | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1985-11-12 | — | — | US | disclosed |
| US-4511728-A | Silanes and compositions prepared therefrom | CONSORTIUM FUR ELEKTROCHEMISCHE (DE) | 1985-04-16 | — | — | US | disclosed |
| EP-0089618-A1 | Silanes and compositions prepared by making use of the silanes | Consortium für elektrochemische Industrie GmbH (DE) | 1983-09-28 | — | — | EP | disclosed |