Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 13/20 | 0.62 |
| ▸ | ERCC4 | Q92889 | 13/20 | 0.62 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507183 | 0.80 | ERCC1 (0.62) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL107157 | 0.80 | ERCC1 (0.76) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL6178238 | 0.78 | HPGD (0.68) | — | |
| SCHEMBL175299 | 0.72 | ERCC1 (0.66) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL107288 | 0.72 | ERCC1 (0.66) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL14081427 | 0.71 | ERCC1 (0.60) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL8269527 | 0.70 | KDM4E (0.69) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL107165 | 0.70 | ERCC1 (0.73) | ERCC1ERCC4TRPV1 | |
| SCHEMBL8483573 | 0.69 | ERCC1 (0.59) | ERCC1ERCC4ALPGALPLTRPV1 | |
| SCHEMBL23796256 | 0.69 | ERCC1 (0.63) | ERCC1ERCC4ALPGALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291345-B1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |