SCHEMBL8508530

SCHEMBL8508530

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)OCC(O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 1.00
ENPP2 Q13822 8/20 1.00
LPAR3 Q9UBY5 6/20 1.00
LPAR4 Q99677 3/20 1.00
LPAR5 Q9H1C0 3/20 1.00
LPAR2 Q9HBW0 3/20 1.00
LPAR6 P43657 2/20 1.00
CES2 O00748 1/20 0.85
TRPV1 Q8NER1 1/20 0.85
SMN1; SMN2 Q16637 1/20 0.70
P2RY10 O00398 3/20 0.68
GPR174 Q9BXC1 3/20 0.68
GPR34 Q9UPC5 2/20 0.68
GPR55 Q9Y2T6 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6362553 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8508094 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL13043253 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL2935599 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL2936577 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8509455 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8736955 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8509038 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL2935665 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8507661 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906759-A1 Novel osteoblastic specific mitogenes: process for their preparation and drugs containing these compounds Roche Diagnostics GmbH (DE) 1999-04-07 EP disclosed