SCHEMBL2935665

SCHEMBL2935665

CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 1.00
ENPP2 Q13822 8/20 1.00
LPAR3 Q9UBY5 6/20 1.00
LPAR4 Q99677 3/20 1.00
LPAR5 Q9H1C0 3/20 1.00
LPAR2 Q9HBW0 3/20 1.00
LPAR6 P43657 2/20 1.00
CES2 O00748 1/20 0.85
TRPV1 Q8NER1 1/20 0.85
SMN1; SMN2 Q16637 1/20 0.70
P2RY10 O00398 3/20 0.68
GPR174 Q9BXC1 3/20 0.68
GPR34 Q9UPC5 2/20 0.68
GPR55 Q9Y2T6 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6362553 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8508094 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL13043253 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL2935599 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL2936577 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8508530 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8509455 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8736955 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8509038 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5
SCHEMBL8507661 1.00 LPAR1 (1.00) LPAR1ENPP2LPAR3LPAR4LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064521-A Method for identifying organic phosphate and application thereof 中山大学 2025-05-30 CN claimed
CN-118178324-B FAP alpha hydrolysis charge-turned liposome and composition, and preparation method and application thereof 锐康九域(厦门)医药科技有限公司 2025-02-07 CN claimed
CN-120064521-A Method for identifying organic phosphate and application thereof 中山大学 2025-05-30 CN disclosed
EP-4515242-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN Pharmaceutica NV (BE) 2025-03-05 EP disclosed
US-20250037787-A1 CONCENTRATION BOUNDS IN LARGE NETWORKS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-30 US disclosed
WO-2023209218-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2023-11-02 WO disclosed
US-20170254822-A1 METHODS AND KITS FOR DETECTING AND DIAGNOSING NEUROTRAUMA APOLLO ENDOSURGERY, INC. 2017-09-07 US disclosed
US-20170254822-A1 METHODS AND KITS FOR DETECTING AND DIAGNOSING NEUROTRAUMA APOLLO ENDOSURGERY, INC. 2017-09-07 US disclosed
US-20170114125-A1 METHODS OF TREATING DISEASE USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID APOLLO ENDOSURGERY INTERNATIONAL, LLC 2017-04-27 US disclosed
US-20170114125-A1 METHODS OF TREATING DISEASE USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID APOLLO ENDOSURGERY INTERNATIONAL, LLC 2017-04-27 US disclosed
US-20170088634-A1 TREATMENT OF NEUROTRAUMA USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID APOLLO ENDOSURGERY, INC. 2017-03-30 US disclosed
US-20080145360-A1 Lysolipid specific immunoglobulin for use in diagnosis, prevention and treatment of blood and cell proliferative disorders INNOVATUS LIFE SCIENCES LENDING FUND I, LP 2008-06-19 US disclosed
US-20080138334-A1 Immune-Derived Moieties Reactive Against Bioactive Lipids, and Methods of Making and Using Same SABBADINI ROGER A 2008-06-12 US disclosed
US-20080138334-A1 Immune-Derived Moieties Reactive Against Bioactive Lipids, and Methods of Making and Using Same SABBADINI ROGER A 2008-06-12 US disclosed
US-20080090303-A1 Methods and Reagents for Detecting Bioactive Lipids APOLLO ENDOSURGERY, INC. 2008-04-17 US disclosed
US-20080090303-A1 Methods and Reagents for Detecting Bioactive Lipids APOLLO ENDOSURGERY, INC. 2008-04-17 US disclosed
US-20070281320-A1 Novel Bioactive Lipid Derivatives, and Methods of Making and Using Same INNOVATUS LIFE SCIENCES LENDING FUND I, LP 2007-12-06 US disclosed
US-20070280933-A1 Methods for decreasing immune response and treating immune conditions APOLLO ENDOSURGERY, INC. 2007-12-06 US disclosed
US-20070148168-A1 Compositions and methods for the treatment and prevention of fibrotic, inflammatory and neovascularization conditions LPATH, INC. 2007-06-28 US disclosed
US-20070148168-A1 Compositions and methods for the treatment and prevention of fibrotic, inflammatory and neovascularization conditions LPATH, INC. 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070280933-A1 Methods for decreasing immune response and treating immune conditions LPAR1, LPAR2, S1PR1 LPAR1 1/4885ENPP2 19/4885LPAR3 10/4885
US-20170114125-A1 METHODS OF TREATING DISEASE USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID LPAR5, LPAR2, LPAR6 LPAR1 5/4885ENPP2 9/4885LPAR3 6/4885
US-20080145360-A1 Lysolipid specific immunoglobulin for use in diagnosis, prevention and treatment of blood and cell proliferative disorders CD47, SGMS1, ALG1 LPAR1 5/4885ENPP2 67/4885LPAR3 11/4885
US-20170088634-A1 TREATMENT OF NEUROTRAUMA USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID LPAR4, LPAR5, LPAR1 LPAR1 3/4885ENPP2 47/4885LPAR3 7/4885
US-20070281320-A1 Novel Bioactive Lipid Derivatives, and Methods of Making and Using Same SGMS1, SGMS2, LPAR1 LPAR1 3/4885ENPP2 93/4885LPAR3 7/4885
US-20080138334-A1 Immune-Derived Moieties Reactive Against Bioactive Lipids, and Methods of Making and Using Same CD47, ALG1, SGMS1 LPAR1 4/4885ENPP2 73/4885LPAR3 7/4885
US-20070148168-A1 Compositions and methods for the treatment and prevention of fibrotic, inflammatory and neovascularization conditions S1PR1, S1PR5, S1PR3 LPAR1 9/4885ENPP2 21/4885LPAR3 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.