SCHEMBL8508552

SCHEMBL8508552

CC[C@H](C)C[SiH2]C[C@@H](C)CC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6651707 1.00 TSHR (0.33) TSHR
SCHEMBL8726076 1.00 TSHR (0.33) TSHR
SCHEMBL8727735 0.91
SCHEMBL8531466 0.91
SCHEMBL8722001 0.87
SCHEMBL8508514 0.87
SCHEMBL8511883 0.84
SCHEMBL8510752 0.80 TSHR (0.31) TSHR
SCHEMBL8510104 0.78 TSHR (0.33) TSHR
SCHEMBL8508578 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612756-B1 Organosilicon compounds NIPPON TELEGRAPH & TELEPHONE (JP) 1999-04-28 EP disclosed
US-5710301-A Organosilicon compounds NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-01-20 US disclosed
EP-0612756-A1 Organosilicon compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-08-31 EP disclosed