SCHEMBL8510752

SCHEMBL8510752

CCCC[SiH2]C[C@@H](C)CC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
TRPM8 Q7Z2W7 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8510104 0.92 TSHR (0.33) TSHRTRPM8
SCHEMBL8509106 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8508152 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8508815 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8508681 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8508577 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL2143999 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8511643 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8510716 0.90 TSHR (0.38) TSHRTRPM8
SCHEMBL8511883 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612756-B1 Organosilicon compounds NIPPON TELEGRAPH & TELEPHONE (JP) 1999-04-28 EP disclosed
US-5710301-A Organosilicon compounds NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-01-20 US disclosed
EP-0612756-A1 Organosilicon compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-08-31 EP disclosed