Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143999 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8508815 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8510716 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8508681 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8511643 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8509106 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8508152 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8510104 | 0.98 | TSHR (0.33) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL8510752 | 0.90 | TSHR (0.31) | TSHRTRPM8 | |
| SCHEMBL8722908 | 0.80 | TSHR (0.42) | TSHRTHRBDNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612756-B1 | Organosilicon compounds | NIPPON TELEGRAPH & TELEPHONE (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-5710301-A | Organosilicon compounds | NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0612756-A1 | Organosilicon compounds | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1994-08-31 | — | — | EP | disclosed |