SCHEMBL8510200

SCHEMBL8510200

CCONC(=O)CC(=O)C1=C(O)CC(c2c(C)cc(C)cc2C)CC1=O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.32
LDHA P00338 2/20 0.32
LMNA P02545 1/20 0.32
NR2F2 P24468 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091912 0.82 RAB9A (0.40) RAB9ALDHALMNANR2F2MEN1
SCHEMBL10682228 0.80 MEN1 (0.39) RAB9ALDHALMNANR2F2MEN1
SCHEMBL10683366 0.74 RAB9A (0.40) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL8535129 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL8535128 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL9706912 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL16713734 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL336503 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL54230 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A
Tralkoxydim SCHEMBL54229 0.74 RAB9A (0.46) RAB9ALDHALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333131-B1 Plant protective agent based on pyrazolecarboxylic acid derivatives HOECHST AG (DE) 1993-10-27 EP claimed
EP-0333131-A1 Plant protective agent based on pyrazolecarboxylic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-20 EP claimed
US-5945541-A Plant protection agents based on pyrazolecarboxylic acid derivatives HOECHST SCHERING AGREVO GMBH (DE) 1999-08-31 US disclosed
EP-0635996-B1 PYRAZOLINES FOR THE PROTECTION OF CROP PLANTS AGAINST HERBICIDES HOECHST SCHERING AGREVO GMBH (DE) 1998-02-11 EP disclosed
US-5703008-A Pyrazolines for protecting crop plants against herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5700758-A APPLYING TO SAFEN PLANTS AGAINST PHOTOTOXICITY HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-23 US disclosed
US-5401700-A Plant protection agents based on pyrazolecarboxylic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-28 US disclosed
EP-0635996-A1 PYRAZOLINES FOR THE PROTECTION OF CROPS AGAINST HERBICIDES Hoechst Schering AgrEvo GmbH (DE) 1995-02-01 EP disclosed
EP-0409118-B1 Pyrazolines and their use as antidotes HOECHST SCHERING AGREVO GMBH (DE) 1994-10-12 EP disclosed
EP-0333131-B1 Plant protective agent based on pyrazolecarboxylic acid derivatives HOECHST AG (DE) 1993-10-27 EP disclosed
EP-0254222-B1 QUINOLINOXY COMPOUNDS, PROCEDURE FOR THEIR SYNTHESIS AND THEIR APPLICATION AS ANTIDOTES HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-26 EP disclosed
WO-1991007874-A1 PYRAZOLINES FOR THE PROTECTION OF CROPS AGAINST HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-13 WO disclosed
EP-0431545-A2 Selectif herbicidal agent and fungicidal agent Hoechst Schering AgrEvo GmbH (DE) 1991-06-12 EP disclosed
EP-0269806-B1 PHENYLPYRAZOLE CARBONIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS AND ANTIDOTES HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-27 EP disclosed
EP-0409118-A1 Pyrazolines and their use as antidotes Hoechst Schering AgrEvo GmbH (DE) 1991-01-23 EP disclosed
US-4925478-A PLANT SAFENING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4891057-A Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 US disclosed
EP-0333131-A1 Plant protective agent based on pyrazolecarboxylic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-20 EP disclosed
EP-0269806-A1 Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-08 EP disclosed
EP-0254222-A2 Quinolinoxy compounds, procedure for their synthesis and their application as antidotes HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-27 EP disclosed