Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508225 | 0.82 | SPR (0.31) | SPR | |
| SCHEMBL8508612 | 0.80 | SPR (0.41) | MAPTTP53THRBSPRLMNA | |
| SCHEMBL8564605 | 0.80 | — | — | |
| SCHEMBL8508339 | 0.79 | SPR (0.38) | MAPTTP53THRBSPRLMNA | |
| SCHEMBL8509170 | 0.73 | MAPT (0.34) | MAPTTP53THRBSPRLMNA | |
| SCHEMBL8346483 | 0.70 | GCK (0.32) | — | |
| SCHEMBL8724298 | 0.68 | SPR (0.47) | SPRRAB9A | |
| SCHEMBL8509803 | 0.67 | SPR (0.55) | SPR | |
| SCHEMBL30824710 | 0.66 | NAMPT (0.41) | MAPTNPC1RAB9A | |
| SCHEMBL8122941 | 0.64 | GCK (0.31) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985799-A | TRICYCLIC N-HETEROCYCLES, THEIR N-OXIDES, AGRICULTURALLY-SUITABLE SALTS AND COMPOSITIONS, AND METHODS OF THEIR USE FOR CONTROLLING UNDESIRABLE VEGETATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-16 | — | — | US | disclosed |