Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IL18 | Q14116 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411450 | 0.86 | CTNNB1 (0.66) | CTNNB1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL7690228 | 0.86 | CTNNB1 (0.68) | CTNNB1MAPTSLC6A4PARP15PARP10 | |
| SCHEMBL851003 | 0.83 | HTT (0.51) | CTNNB1HTTCCR2ALDH1A1KDM4E | |
| SCHEMBL9252102 | 0.83 | CTNNB1 (0.67) | CTNNB1MAPTHTTALDH1A1PARP10 | |
| SCHEMBL1798 | 0.82 | CTNNB1 (0.71) | CTNNB1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL28011389 | 0.82 | FFAR1 (0.45) | MAPTSLC6A4PARP15PARP10PARP2 | |
| SCHEMBL8496446 | 0.81 | CTNNB1 (0.69) | CTNNB1MAPTHTTALDH1A1KDM4E | |
| Bicarbonate SCHEMBL21517637 | 0.81 | CTNNB1 (0.69) | CTNNB1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL11875755 | 0.81 | CTNNB1 (0.69) | CTNNB1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL4129945 | 0.81 | CTNNB1 (0.69) | CTNNB1MAPTHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |