Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | PYGM | P11217 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | STK10 | O94804 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728621 | 0.87 | HTT (0.45) | HTTKDM4EPOLBPYGLPYGM | |
| SCHEMBL7695689 | 0.87 | CTNNB1 (0.62) | ALDH1A1KDM4ECTNNB1EPAS1VEGFA | |
| SCHEMBL28949714 | 0.87 | CTNNB1 (0.43) | HTTCTNNB1PYGLPYGMEPAS1 | |
| SCHEMBL28949718 | 0.85 | ALDH1A1 (0.43) | HTTALDH1A1CTNNB1PYGLPYGM | |
| SCHEMBL18772927 | 0.85 | AR (0.45) | HTTALDH1A1KDM4EPOLBEPAS1 | |
| SCHEMBL28560551 | 0.84 | KDM4E (0.63) | HTTALDH1A1KDM4EPOLBCTNNB1 | |
| SCHEMBL28011402 | 0.83 | XDH (0.46) | HTTKDM4EPOLBPYGLPYGM | |
| SCHEMBL851138 | 0.83 | CTNNB1 (0.51) | HTTCCR2ALDH1A1KDM4EPOLB | |
| SCHEMBL28264707 | 0.82 | KDM4E (0.61) | HTTALDH1A1KDM4EPOLBCTNNB1 | |
| SCHEMBL8432193 | 0.82 | AR (0.55) | SLC22A12EPAS1STK10SLKVEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |