Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.47 |
| ▸ | CTSG | P08311 | 5/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.47 |
| ▸ | CMA1 | P23946 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511582 | 1.00 | POLB (0.51) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL8511586 | 1.00 | POLB (0.51) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL10788978 | 0.88 | POLB (0.53) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL28128466 | 0.78 | POLB (0.53) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL10438916 | 0.78 | POLB (0.50) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL9986715 | 0.77 | CES1 (0.51) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL7807968 | 0.76 | POLB (0.45) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL17284037 | 0.76 | SMN1; SMN2 (0.52) | POLBSRCSMN1; SMN2KCNN4RAB9A | |
| SCHEMBL22780388 | 0.76 | POLB (0.69) | POLBSRCPRSS1CTSGCTRB1 | |
| SCHEMBL14459975 | 0.76 | POLB (0.47) | POLBSRCPRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994312-A | Peptidyl compounds | DARWIN DISCOVERY, LTD. (GB) | 1999-11-30 | — | — | US | disclosed |