Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.61 |
| ▸ | PTPRC | P08575 | 1/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | RXRB | P28702 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045708 | 1.00 | PARP10 (0.61) | PARP10PTPRCPTPN2PTPN1NR4A2 | |
| SCHEMBL12045717 | 0.87 | PTPRC (0.63) | PARP10PTPRCPTPN1NR4A2NR4A1 | |
| SCHEMBL851386 | 0.83 | MAPT (0.53) | PARP10MAOBRAB9APRSS1 | |
| SCHEMBL12045721 | 0.83 | L3MBTL1 (0.41) | PARP10PTPRCPTPN2PTPN1NR4A2 | |
| SCHEMBL839231 | 0.80 | NR4A2 (0.60) | PTPN1NR4A2NR4A1NR4A3MAOB | |
| SCHEMBL28516246 | 0.80 | PARP10 (0.59) | PARP10MAOBNPC1RAB9AMAOA | |
| SCHEMBL841269 | 0.80 | GAA (0.59) | MAOBMAOAF2PRSS1ST14 | |
| SCHEMBL839292 | 0.79 | RARB (0.49) | PARP10MAOBRAB9APRSS1 | |
| SCHEMBL8134318 | 0.77 | NR4A2 (0.85) | PARP10PTPRCPTPN2PTPN1NR4A2 | |
| SCHEMBL23067275 | 0.77 | SMN1; SMN2 (0.52) | RXRANPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143465-B2 | Soluble branched triaroylbenzene-based polymer and its synthetic method | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2012-03-27 | — | — | US | disclosed |