Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159761 | 0.89 | KMT2A (0.57) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL4428377 | 0.89 | MAPT (0.55) | KMT2ALMNAMRGPRX4MAPT | |
| SCHEMBL4425326 | 0.88 | KDM4E (0.59) | MRGPRX4MAPTRAB9AKDM4ECYP1A2 | |
| SCHEMBL3960907 | 0.87 | KMT2A (0.62) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL229472 | 0.87 | MRGPRX4 (0.69) | KMT2ALMNAMRGPRX4RAB9APTGER1 | |
| SCHEMBL30141105 | 0.87 | KMT2A (0.62) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL6693656 | 0.85 | KMT2A (0.64) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL27725945 | 0.85 | KMT2A (0.53) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL7127765 | 0.84 | MAPT (0.52) | LMNAMRGPRX4MAPTRAB9ANPC1 | |
| SCHEMBL7127771 | 0.84 | MAPT (0.52) | LMNAMRGPRX4MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254135-A1 | POLYPHENOL COMPOUNDS | EPIRIUM BIO INC (US) | 2024-08-01 | — | — | US | disclosed |
| EP-2643310-A1 | 4- (5-CYANO-PYRAZOL-1-YL) -PIPERIDINE DERIVATIVES AS GPR 119 MODULATORS | Pfizer Inc (US) | 2013-10-02 | — | — | EP | disclosed |
| CN-103298801-A | 4- (5-cyano-pyrazol-1-yl) -piperidine derivatives as GPR 119 modulators | PFIZER | 2013-09-11 | — | — | CN | disclosed |
| WO-2012069948-A1 | 4- (5-CYANO-PYRAZOL-1-YL) -PIPERIDINE DERIVATIVES AS GPR 119 MODULATORS | PFIZER INC. (US) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254135-A1 | POLYPHENOL COMPOUNDS | COMT, MAPT, PPARG | SLC6A2 305/4885SLC6A3 439/4885KMT2A 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.