Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127765 | 1.00 | MAPT (0.52) | MAPTMRGPRX4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8512033 | 0.84 | SLC6A2 (0.57) | MAPTMRGPRX4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9710281 | 0.81 | MAPT (0.53) | MAPTMRGPRX4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7169198 | 0.78 | ALDH1A1 (0.51) | MAPTMRGPRX4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7169194 | 0.78 | ALDH1A1 (0.51) | MAPTMRGPRX4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7126411 | 0.78 | MRGPRX4 (0.47) | MRGPRX4SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9484001 | 0.78 | MAPT (0.59) | MAPTSMN1; SMN2RAB9AADRB2ADRB1 | |
| SCHEMBL9456235 | 0.78 | MAPT (0.59) | MAPTSMN1; SMN2RAB9AADRB2ADRB1 | |
| SCHEMBL6937628 | 0.78 | MAPT (0.59) | MAPTSMN1; SMN2RAB9AADRB2ADRB1 | |
| SCHEMBL4747320 | 0.78 | MAOB (0.59) | MAPTMRGPRX4SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6666989-B1 | Electrical and electro-optic apparatus comprising spaced glass panels having polyethers and electrodes on the interior surfaces, used as detectors, screens and in nonlinear optical apparatus | QINETIQ LIMITED (GB) | 2003-12-23 | — | — | US | disclosed |