Leucine

Leucine

SCHEMBL8513294

CC(C)C[C@H](N)C(=O)O.N[C@@H](COC(=O)[C@@H](N)Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.57
ALPI P09923 1/20 0.57
PKM P14618 1/20 0.57
PTGS1 P23219 1/20 0.57
XIAP P98170 1/20 0.57
ANPEP P15144 3/20 0.56
RNPEP Q9H4A4 2/20 0.56
DNPEP Q9ULA0 2/20 0.56
SLC1A1 P43005 2/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
LTA4H P09960 1/20 0.52
IDO1 P14902 2/20 0.50
SLC1A5 Q15758 1/20 0.46
SLC15A1 P46059 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL8975267 0.94 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3859116 0.90 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
Leucine SCHEMBL11683482 0.89 SLC7A5 (0.57) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL17113860 0.88 SLC7A5 (0.68) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine Methyl Ester SCHEMBL6748761 0.87 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL18870210 0.87 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL208388 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2634732 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10945389 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL10775923 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296500-A1 Methods and Compositions of Nucleic Acid Ligands for Detection of Clinical Analytes Related to Human Health OTC BIOTECHNOLOGIES, LLC (US) 2014-10-02 US disclosed
US-8658613-B2 Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health OTC BIOTECHNOLOGIES, LLC (US) 2014-02-25 US disclosed
US-20120135540-A1 Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health OTC BIOTECHNOLOGIES, LLC 2012-05-31 US disclosed