Phenylalanine

Phenylalanine

SCHEMBL8975267

CC(C)C[C@H](N)C(=O)OC[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.61
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
PTGS1 P23219 1/20 0.61
XIAP P98170 1/20 0.61
ANPEP P15144 2/20 0.56
RNPEP Q9H4A4 2/20 0.56
DNPEP Q9ULA0 2/20 0.56
LTA4H P09960 1/20 0.52
SLC1A1 P43005 2/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
IDO1 P14902 1/20 0.50
SLC1A5 Q15758 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leucine SCHEMBL8513294 0.94 SLC7A5 (0.57) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL11683484 0.89 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL208388 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL10775923 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL208389 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10945389 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3859116 0.87 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL31087886 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2634732 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL28157585 0.87 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500208-A Oral compositions comprising a novel tripeptide THE PROCTER & GAMBLE COMPANY (US) 1996-03-19 US claimed
EP-0248838-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) 1987-12-16 EP claimed
WO-1987003485-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDER (NL) 1987-06-18 WO claimed
EP-0703899-A1 ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-04-03 EP disclosed
US-5500208-A Oral compositions comprising a novel tripeptide THE PROCTER & GAMBLE COMPANY (US) 1996-03-19 US disclosed
WO-1995033764-A2 ORAL COMPOSITIONS COMPRISING A NOVEL TRIPEPTIDE PROCTER & GAMBLE (US) 1995-12-14 WO disclosed
EP-0248838-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) 1987-12-16 EP disclosed
WO-1987003485-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDER (NL) 1987-06-18 WO disclosed