Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KHK | P50053 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922775 | 0.87 | USP2 (0.58) | ALDH1A1TSHRHSD17B10USP2HPGD | |
| SCHEMBL3770301 | 0.84 | NPC1 (0.47) | ALDH1A1TSHRHSD17B10USP2MAPT | |
| SCHEMBL22802008 | 0.84 | NPC1 (0.47) | ALDH1A1TSHRHSD17B10USP2MAPT | |
| SCHEMBL3770299 | 0.84 | NPC1 (0.47) | ALDH1A1TSHRHSD17B10USP2MAPT | |
| SCHEMBL15378488 | 0.83 | KHK (0.57) | ALDH1A1HSD17B10MAPTLMNAALOX15 | |
| SCHEMBL4246310 | 0.83 | KHK (0.57) | ALDH1A1HSD17B10MAPTLMNAALOX15 | |
| SCHEMBL4246315 | 0.83 | KHK (0.57) | ALDH1A1HSD17B10MAPTLMNAALOX15 | |
| SCHEMBL8183599 | 0.82 | ACVR1 (0.48) | ALDH1A1TSHRHSD17B10USP2MAPT | |
| Hydrochloric Acid SCHEMBL15819287 | 0.81 | KHK (0.56) | ALDH1A1HSD17B10MAPTLMNAALOX15 | |
| SCHEMBL5268403 | 0.80 | KHK (0.52) | ALDH1A1TSHRHSD17B10USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139552-B2 | Indeno-fused naphthopyrans having ethylenically unsaturated groups | TRANSITIONS OPTICAL, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| WO-2013090220-A1 | INDENO-FUSED NAPHTHOPYRANS HAVING ETHYLENICALLY UNSATURATED GROUPS | PPG INDUSTRIES, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | TRANSITIONS OPTICAL INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | ACR, INTS6, B3GNT2 | ALDH1A1 318/4885TSHR 4437/4885HSD17B10 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.