SCHEMBL8513403

SCHEMBL8513403

CC(Br)C(=S)OCc1ccco1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
LMNA P02545 1/20 0.46
KMT2A Q03164 4/20 0.41
MAPK1 P28482 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 3/20 0.40
TP53 P04637 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP2D6 P10635 1/20 0.40
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
POLB P06746 3/20 0.39
TSHR P16473 1/20 0.39
GAA P10253 4/20 0.38
MEN1 O00255 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8515458 0.82 ALDH1A1 (0.65) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL526873 0.78 ALDH1A1 (0.68) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL2266382 0.75 ALDH1A1 (0.69) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL29393704 0.75 ALDH1A1 (0.59) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL28299288 0.74 ALDH1A1 (0.58) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL14655669 0.72 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL7380721 0.71 ALDH1A1 (0.54) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL1532474 0.71 ALDH1A1 (0.63) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL11339548 0.71 ALDH1A1 (0.63) ALDH1A1LMNAKMT2AMAPK1TDP1
SCHEMBL20982040 0.71 ALDH1A1 (0.54) ALDH1A1LMNAKMT2AMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235880-B1 PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED CARBON BLACK PARTICLES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2018-11-14 EP disclosed
EP-2643414-B1 PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED SILICA PARTICLES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2018-11-07 EP disclosed
EP-3235880-A1 PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED FILLER PARTICLES Continental Reifen Deutschland GmbH (DE) 2017-10-25 EP disclosed
CN-103221490-B For the production of the method for the filler particles of functionalization of polymers CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2015-08-12 CN disclosed
US-8912267-B2 Process for producing polymer-functionalized filler particles CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2014-12-16 US disclosed
US-20130261272-A1 PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED FILLER PARTICLES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2013-10-03 US disclosed
EP-2643414-A2 PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED FILLER PARTICLES Continental Reifen Deutschland GmbH (DE) 2013-10-02 EP disclosed
CN-103221490-A Process for producing polymer-functionalized filler particles CONTINENTAL REIFEN DEUTSCHLAND 2013-07-24 CN disclosed
WO-2012069403-A2 PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED FILLER PARTICLES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2012-05-31 WO disclosed