Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.63 |
| ▸ | CES1 | P23141 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572867 | 1.00 | CES2 (0.63) | CES2CES1LMNAMAPK1BLM | |
| SCHEMBL1572839 | 1.00 | CES2 (0.63) | CES2CES1LMNAMAPK1BLM | |
| Hydrochloric Acid SCHEMBL7248840 | 0.98 | CES2 (0.61) | CES2CES1LMNAMAPK1BLM | |
| Hydrochloric Acid SCHEMBL7248837 | 0.98 | CES2 (0.61) | CES2CES1LMNAMAPK1BLM | |
| SCHEMBL23972859 | 0.86 | CES2 (0.48) | CES2CES1LMNAMAPK1BLM | |
| SCHEMBL23972406 | 0.82 | CES2 (0.46) | CES2CES1LMNAMAPK1 | |
| SCHEMBL3344127 | 0.80 | CES2 (0.47) | CES2CES1LMNA | |
| SCHEMBL7374087 | 0.80 | CES2 (0.47) | CES2CES1LMNA | |
| SCHEMBL3344038 | 0.80 | CES2 (0.47) | CES2CES1LMNA | |
| SCHEMBL8313497 | 0.79 | CES2 (0.61) | CES2CES1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-113355367-B | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-113355299-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113355367-A | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | claimed |
| CN-113355299-A | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | claimed |
| CN-108410831-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-07-27 | — | — | CN | claimed |
| CN-108410831-A | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2018-08-17 | — | — | CN | claimed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | claimed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | claimed |
| EP-4142874-B1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2026-04-22 | — | — | EP | disclosed |
| US-12590064-B2 | Substituted benzamides for inhibiting perk activity | ELI LILLY AND COMPANY (US) | 2026-03-31 | — | — | US | disclosed |
| EP-4688746-A1 | CRYSTALLINE FORMS OF (R)-2-AMINO-5-(4-(2-(3,5-DIFLUOROPHENYL)-2-HYDROXYACETAMIDO)-2-METHYLPHENYL)-N-ISOPROPYLNICOTINAMIDE AND METHODS FOR USING THE SAME | Hibercell, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |
| US-12473296-B2 | Perk inhibiting compounds | HIBERCELL, INC. (US) | 2025-11-18 | — | — | US | disclosed |
| WO-1997002284-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | ASTRA AKTIEBOLAG (SE) | 1997-01-23 | — | — | WO | disclosed |
| CN-1022913-C | Herbicidal compositions containing new pyrrolidine derivative and its preparing method | MITSUI TOATSU CHEMICALS (JP) | 1993-12-01 | — | — | CN | disclosed |
| EP-0387869-B1 | 4-ETHYL-3-(SUBSTITUTED PHENYL)-1-(3-TRIFLUOROMETHYL-PHENYL)-2-PYRROLIDINONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USE THEREOF, HERBICIDAL COMPOSITIONS CONTAINING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5131947-A | 4-ETHYL-3-(SUBSTITUTED PHENYL)-1-(3-TRIFLUOROMETHYLPHENYL)-2-PYRROLIDINONE DERIVATIVES, HERBICIDAL COMPOSITIONS CONTAINING THEM AND USE THEREOF | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1992-07-21 | — | — | US | disclosed |
| CN-1045581-A | 4-ethyl-3-(substituted-phenyl)-1-(3-trifluoromethyl)-2-Pyrrolidone derivative, its preparation method contains the herbicidal composition of this derivative as activeconstituents | MITSUI TOATSU CHEMICALS (JP) | 1990-09-26 | — | — | CN | disclosed |
| EP-0387869-A2 | 4-Ethyl-3-(substituted phenyl)-1-(3-trifluoromethyl-phenyl)-2-pyrrolidinone derivatives, processes for the preparation and use thereof, herbicidal compositions containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473296-B2 | Perk inhibiting compounds | MAPK1, ERN1, MAP3K20 | CES2 1592/4885CES1 282/4885LMNA 1117/4885 |
| US-12590064-B2 | Substituted benzamides for inhibiting perk activity | EIF2AK3, EIF2AK1, EIF2AK4 | CES2 675/4885CES1 1212/4885LMNA 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.