Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687455 | 0.94 | TSHR (0.53) | LTA4HEPHX2TSHRSLC6A4SLC6A3 | |
| SCHEMBL9060027 | 0.92 | TSHR (0.51) | LTA4HEPHX2TSHRSLC6A4SLC6A3 | |
| SCHEMBL9060389 | 0.89 | TSHR (0.49) | TSHRSLC6A4SLC6A3ALDH1A1DAO | |
| SCHEMBL9425491 | 0.89 | TSHR (0.49) | TSHRSLC6A4SLC6A3ALDH1A1DAO | |
| SCHEMBL8990653 | 0.87 | TSHR (0.47) | TSHRSLC6A4SLC6A3ALDH1A1DAO | |
| SCHEMBL8990885 | 0.87 | TSHR (0.47) | TSHRSLC6A4SLC6A3ALDH1A1DAO | |
| SCHEMBL2056132 | 0.86 | TSHR (0.53) | LTA4HEPHX2TSHRSLC6A4SLC6A3 | |
| SCHEMBL8379711 | 0.84 | ACACB (0.52) | TSHRSLC6A4SLC6A3ALDH1A1DAO | |
| SCHEMBL7733396 | 0.84 | TSHR (0.45) | LTA4HEPHX2TSHRSLC6A4SLC6A3 | |
| SCHEMBL9060735 | 0.84 | TSHR (0.45) | TSHRSLC6A4SLC6A3ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |