Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 14/20 | 0.46 |
| ▸ | XIAP | P98170 | 10/20 | 0.46 |
| ▸ | BIRC3 | Q13489 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514034 | 1.00 | BIRC2 (0.46) | BIRC2XIAPBIRC3 | |
| SCHEMBL13017629 | 1.00 | BIRC2 (0.46) | BIRC2XIAPBIRC3 | |
| SCHEMBL8514107 | 0.90 | CTSL (0.38) | BIRC2XIAPBIRC3 | |
| SCHEMBL9613442 | 0.90 | CTSL (0.38) | BIRC2XIAPBIRC3 | |
| SCHEMBL9613480 | 0.84 | XIAP (0.46) | BIRC2XIAPBIRC3 | |
| SCHEMBL8511123 | 0.84 | XIAP (0.46) | BIRC2XIAPBIRC3 | |
| SCHEMBL9613474 | 0.82 | XIAP (0.43) | BIRC2XIAPBIRC3 | |
| SCHEMBL8515048 | 0.82 | XIAP (0.43) | BIRC2XIAPBIRC3 | |
| SCHEMBL8514257 | 0.81 | XIAP (0.43) | BIRC2XIAPBIRC3 | |
| SCHEMBL9613434 | 0.81 | XIAP (0.43) | BIRC2XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415486-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120135990-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135990-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | BIRC2 4/4885XIAP 1/4885BIRC3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.