Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 10/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573666 | 1.00 | POLB (0.47) | POLBL3MBTL1SPHK2SPHK1PARP1 | |
| SCHEMBL2559500 | 0.82 | S1PR1 (0.38) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL29955370 | 0.81 | POLB (0.44) | POLBL3MBTL1SPHK2SPHK1PARP1 | |
| SCHEMBL11300057 | 0.80 | POLB (0.42) | POLBL3MBTL1SPHK2SPHK1 | |
| SCHEMBL8436147 | 0.80 | POLB (0.42) | POLBL3MBTL1SPHK2SPHK1 | |
| SCHEMBL16292754 | 0.77 | SIGMAR1 (0.41) | — | |
| SCHEMBL2268870 | 0.76 | — | — | |
| SCHEMBL14067026 | 0.76 | — | — | |
| SCHEMBL2557418 | 0.76 | SIGMAR1 (0.32) | ALDH1A1 | |
| SCHEMBL30846523 | 0.76 | HDAC8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457903-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2012-05-30 | — | — | EP | claimed |
| CN-114805301-A | 2, 4-diarylaminopyrimidine compounds and preparation method and application thereof | 沈阳药科大学 | 2022-07-29 | — | — | CN | disclosed |