Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055180 | 0.84 | PDE2A (0.47) | TSHRLMNATRPV1PDE2A | |
| SCHEMBL8990775 | 0.82 | DAO (0.41) | SLC6A4TSHRDAOALDH1A1SLC6A3 | |
| SCHEMBL8515213 | 0.81 | SLC6A4 (0.47) | SLC6A4TSHRDAOCYP11B1CYP11B2 | |
| SCHEMBL9061734 | 0.79 | TSHR (0.43) | SLC6A4TSHRDAOALDH1A1LMNA | |
| SCHEMBL7851561 | 0.78 | FFAR1 (0.45) | LMNA | |
| SCHEMBL1687455 | 0.77 | TSHR (0.53) | SLC6A4TSHRDAOALDH1A1LMNA | |
| SCHEMBL7654059 | 0.77 | TAAR1 (0.40) | ALDH1A1ALOX5CNR2LMNA | |
| SCHEMBL2092054 | 0.77 | SLC6A4 (0.56) | SLC6A4TSHRDAOMPOCYP11B1 | |
| SCHEMBL14959716 | 0.76 | ADRB2 (0.44) | MPOLMNATRPV1PDE2A | |
| SCHEMBL8990665 | 0.76 | S1PR1 (0.44) | TSHRDAOALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |