SCHEMBL8515345

SCHEMBL8515345

Nc1ccc(Oc2cccnc2Oc2ccc(N)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
APAF1 O14727 1/20 0.58
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MAOA P21397 2/20 0.45
RAB9A P51151 1/20 0.43
MAPT P10636 3/20 0.42
MITF O75030 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NLRP1 Q9C000 1/20 0.42
NOD2 Q9HC29 1/20 0.42
TEAD4 Q15561 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4938450 0.82 TDP1 (0.51) MEN1KMT2AALDH1A1TDP1TSHR
SCHEMBL8513869 0.81 MAOB (0.50) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL13282548 0.80 MEN1 (0.56) MEN1KMT2AAPAF1ALDH1A1TDP1
SCHEMBL580112 0.80 MEN1 (0.56) MEN1KMT2AAPAF1ALDH1A1TDP1
SCHEMBL15044336 0.80 MEN1 (0.56) MEN1KMT2AAPAF1ALDH1A1TDP1
SCHEMBL13282750 0.80 MEN1 (0.56) MEN1KMT2AAPAF1ALDH1A1TDP1
SCHEMBL2460533 0.80 KMT2A (0.56) MEN1KMT2AAPAF1ALDH1A1TDP1
SCHEMBL4796326 0.80 MEN1 (0.56) MEN1KMT2AAPAF1NCOA1NCOA3
SCHEMBL21186225 0.80 MEN1 (0.56) MEN1KMT2AAPAF1NCOA1NCOA3
SCHEMBL27189021 0.80 MEN1 (0.56) MEN1KMT2AAPAF1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5916488-A Polyimide resin compositions for optical filters MITSUI CHEMICALS, INC. (JP) 1999-06-29 US disclosed
US-5868968-A Polyimide resin compositions for optical filters MITSUI CHEMICALS, INC. (JP) 1999-02-09 US disclosed
EP-0695955-A2 Polyimide resin compositions for optical filters MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-02-07 EP disclosed