Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013708 | 1.00 | P2RX7 (1.00) | P2RX7KMT2A | |
| SCHEMBL2579502 | 0.89 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2579503 | 0.89 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2578453 | 0.86 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2578459 | 0.86 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3287222 | 0.84 | P2RX7 (1.00) | P2RX7KMT2A | |
| SCHEMBL3287224 | 0.84 | P2RX7 (1.00) | P2RX7KMT2A | |
| SCHEMBL2582331 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2582324 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3287780 | 0.81 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049478-B1 | SUBSTITUTED N-PHENYLMETHYL -5-OXO-PROLINE-2-AMIDES AS P2X7-RECEPTOR ANTAGONISTS AND THEIR METHODS OF USE | GLAXO GROUP LTD (GB) | 2012-05-30 | — | — | EP | disclosed |