Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764816 | 0.88 | PIK3CA (0.38) | PIK3CACREBBP | |
| SCHEMBL3762884 | 0.87 | PIK3CA (0.45) | PIK3CACREBBP | |
| SCHEMBL855544 | 0.87 | PIK3CA (0.40) | PIK3CACREBBP | |
| SCHEMBL8533202 | 0.86 | PIK3CA (0.40) | PIK3CACREBBP | |
| SCHEMBL856227 | 0.84 | PIK3CA (0.33) | PIK3CACREBBP | |
| SCHEMBL861940 | 0.84 | PIK3CA (0.32) | PIK3CACREBBP | |
| SCHEMBL3767993 | 0.83 | PIK3CA (0.38) | PIK3CACREBBP | |
| SCHEMBL13081733 | 0.82 | PIK3CA (0.41) | PIK3CACREBBP | |
| SCHEMBL8537955 | 0.82 | PIK3CA (0.42) | PIK3CACREBBP | |
| SCHEMBL3760829 | 0.82 | PIK3CA (0.41) | PIK3CACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643315-A1 | BENZOXAZEPINES AS INHIBITORS OF P13K/mTOR AND METHODS OF THEIR USE AND MANUFACTURE | Exelixis, Inc. (US) | 2013-10-02 | — | — | EP | claimed |
| WO-2012071501-A1 | BENZOXAZEPINES ASN INHIBITORS OF P13K/M TOR AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2012-05-31 | — | — | WO | claimed |