Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757624 | 0.89 | PIK3CA (0.31) | PIK3CACREBBP | |
| SCHEMBL856227 | 0.89 | PIK3CA (0.33) | PIK3CACREBBP | |
| SCHEMBL861939 | 0.88 | PIK3CA (0.33) | PIK3CACREBBP | |
| SCHEMBL8533202 | 0.85 | PIK3CA (0.40) | PIK3CACREBBP | |
| SCHEMBL3762884 | 0.84 | PIK3CA (0.45) | PIK3CACREBBP | |
| SCHEMBL855544 | 0.84 | PIK3CA (0.40) | PIK3CACREBBP | |
| SCHEMBL8516266 | 0.84 | PIK3CA (0.38) | PIK3CACREBBP | |
| SCHEMBL3767993 | 0.82 | PIK3CA (0.38) | PIK3CACREBBP | |
| SCHEMBL3760365 | 0.80 | PIK3CD (0.30) | — | |
| SCHEMBL3755339 | 0.80 | PIK3CA (0.39) | PIK3CACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432779-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | Exelixis, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135524-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |