SCHEMBL8516272

SCHEMBL8516272

CCCCCS(=O)(=O)Nc1ccccc1C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324446 0.99 KDM4E (0.53) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL1490973 0.90 KCNA5 (0.59) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL11667006 0.88
SCHEMBL8609056 0.87
SCHEMBL894866 0.86
SCHEMBL26247587 0.86
SCHEMBL26247580 0.86
SCHEMBL30585369 0.86
SCHEMBL897672 0.86
SCHEMBL26247584 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115943143-A 1-pyrazinylpyrazolyl-3-oxyalkyl acids and derivatives thereof and their use for controlling undesired vegetation 拜耳公司 2023-04-07 CN disclosed
CN-115135152-A 1, 5-diphenylpyrazolyl-3-oxyalkyl acids and 1-phenyl-5-thienylpyrazolyl-3-oxyalkyl acids and their use for controlling undesired vegetation 拜耳公司 2022-09-30 CN disclosed
CN-114071999-A 1-phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling undesired vegetation 拜耳公司 2022-02-18 CN disclosed
WO-1999047494-A1 NOVEL BIS-BENZAMIDE DERIVATIVES, METHOD FOR MAKING SAME PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE THEREOF AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 1999-09-23 WO disclosed
EP-0831800-A4 ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS DIMENSIONAL PHARM INC (US) 1999-03-10 EP disclosed
US-5741819-A THROMBOSIS INHIBITORS; ANTIINFLAMMATORY AGENTS; NEURODEGENERATIVE DISORDERS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1998-04-21 US disclosed
EP-0831800-A1 ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1998-04-01 EP disclosed
WO-1996040100-A1 ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
WO-1996039380-A1 BIS-ARYLSULFONYLAMINOBENZAMIDE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1996-12-12 WO disclosed