Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 16/20 | 0.52 |
| ▸ | FPR3 | P25089 | 2/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438108 | 0.88 | CRHR1 (0.56) | CRHR1FPR3TSPOTMEM97ALDH1A1 | |
| SCHEMBL7902814 | 0.73 | CRHR1 (0.68) | CRHR1TDP1 | |
| SCHEMBL7621313 | 0.71 | CRHR1 (0.47) | CRHR1FPR3TSPOTMEM97ALDH1A1 | |
| SCHEMBL7916250 | 0.69 | CRHR1 (0.55) | CRHR1FPR3TSPOTMEM97TDP1 | |
| SCHEMBL8498539 | 0.68 | CRHR1 (0.54) | CRHR1FPR3TSPOTMEM97ALDH1A1 | |
| SCHEMBL9390674 | 0.68 | CRHR1 (0.40) | CRHR1FPR3TSPOTMEM97ALDH1A1 | |
| SCHEMBL16937322 | 0.67 | CRHR1 (0.78) | CRHR1TDP1 | |
| SCHEMBL7645267 | 0.67 | CRHR1 (0.56) | CRHR1FPR3TSPOTMEM97ALDH1A1 | |
| SCHEMBL5611053 | 0.66 | CRHR1 (0.78) | CRHR1FPR3TSPOTMEM97TDP1 | |
| Hydrochloric Acid SCHEMBL25395749 | 0.66 | CRHR1 (0.64) | CRHR1FPR3TSPOTMEM97TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674641-B1 | PYRROLOPYRIMIDINES AS CRF ANTAGONISTS | PFIZER (US) | 1999-03-03 | — | — | EP | claimed |