SCHEMBL8516580

SCHEMBL8516580

CCCCCCCCCCCCOc1ccc(CCCN)cc1C(=O)NCCCCCCN

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.49
ALDH1A1 P00352 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
HTR2A P28223 1/20 0.47
SMPD1 P17405 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
NAAA Q02083 1/20 0.44
PTPN1 P18031 1/20 0.44
PTPN6 P29350 1/20 0.44
PTPN11 Q06124 1/20 0.44
S1PR3 Q99500 1/20 0.44
GHSR Q92847 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9239580 0.99 CNR2 (0.48) CNR2ALDH1A1NPSR1HTR2ASMPD1
SCHEMBL8516689 0.92 ALDH1A1 (0.53) CNR2ALDH1A1NPSR1HDAC3HDAC1
SCHEMBL8369255 0.91 ALDH1A1 (0.47) CNR2ALDH1A1NPSR1HTR2ASMPD1
Hydrochloric Acid SCHEMBL9116966 0.91 ALDH1A1 (0.53) CNR2ALDH1A1NPSR1HDAC3HDAC1
Hydrochloric Acid SCHEMBL9118183 0.90 ALDH1A1 (0.47) CNR2ALDH1A1NPSR1HTR2ASMPD1
SCHEMBL9119461 0.83 PTPN1 (0.46) CNR2ALDH1A1NPSR1SMPD1PTPN1
SCHEMBL8366085 0.83 PTPN11 (0.56) ALDH1A1NPSR1HDAC3HDAC1NAAA
SCHEMBL8367716 0.82 ALDH1A1 (0.70) CNR2ALDH1A1NPSR1HDAC3HDAC1
SCHEMBL15923346 0.82 ALDH1A1 (0.70) CNR2ALDH1A1NPSR1HDAC3HDAC1
Hydrochloric Acid SCHEMBL9116761 0.82 PTPN11 (0.55) ALDH1A1NPSR1HDAC3HDAC1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738144-A4 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORP (US) 1999-06-30 EP disclosed
EP-0891415-A1 CLEANING AGENT WITH OLIGOAMMINE ACTIVATOR COMPLEXES FOR PEROXIDE COMPOUNDS Henkel Kommanditgesellschaft auf Aktien (DE) 1999-01-20 EP disclosed
WO-1997036986-A1 CLEANING AGENT WITH OLIGOAMMINE ACTIVATOR COMPLEXES FOR PEROXIDE COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-10-09 WO disclosed
EP-0738144-A1 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORPORATION (US) 1996-10-23 EP disclosed
WO-1995017888-A1 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORPORATION (US) 1995-07-06 WO disclosed