Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 10/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12245566 | 0.88 | CA12 (0.61) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL13834757 | 0.87 | CA12 (0.74) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL5066331 | 0.86 | CA12 (0.65) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL14695526 | 0.85 | CA12 (0.61) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL15123832 | 0.85 | CA12 (0.61) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL2379660 | 0.85 | CA12 (0.64) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL22140609 | 0.85 | CA12 (0.64) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL2380516 | 0.85 | CA12 (0.64) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL7843204 | 0.85 | CA12 (0.67) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL15123831 | 0.84 | KMT2A (0.65) | CA12CA9ACHEHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067947-A1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | ISCHEMIX LLC (US) | 2012-05-24 | — | — | WO | disclosed |