Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516427 | 0.90 | RAB9A (0.56) | RAB9ATNFNOD1FDPSFADS1 | |
| SCHEMBL8504287 | 0.89 | RAB9A (0.54) | RAB9ATNFNOD1GAAFDPS | |
| SCHEMBL8483529 | 0.88 | MEN1 (0.56) | RAB9ATNFNOD1FDPSHTT | |
| SCHEMBL8491417 | 0.87 | TNF (0.66) | RAB9ATNFNOD1FDPSHTT | |
| SCHEMBL8491611 | 0.84 | RAB9A (0.50) | RAB9ATNFNOD1FDPSHTT | |
| SCHEMBL8504826 | 0.82 | TNF (0.48) | RAB9ATNFNOD1GAAFDPS | |
| SCHEMBL9609197 | 0.81 | RAB9A (0.55) | RAB9ATNFNOD1FDPSFADS1 | |
| SCHEMBL8506789 | 0.81 | RAB9A (0.45) | RAB9ATNFNOD1FDPSFADS1 | |
| SCHEMBL8505245 | 0.81 | RAB9A (0.46) | RAB9ATNFNOD1GAAFDPS | |
| SCHEMBL22862444 | 0.81 | RAB9A (0.76) | RAB9ATNFNOD1GAAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | SDS BIOTECH K.K. (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | CBR3, CBR1, HRH2 | RAB9A 4200/4885TNF 4733/4885NOD1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.