Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPM1 | P06748 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 6/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8367841 | 0.97 | LMNA (0.38) | LMNAHTTPOLBMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL8368538 | 0.92 | CFTR (0.42) | LMNAHTTPOLBMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL8516040 | 0.92 | LMNA (0.37) | LMNAHTTPOLBMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL8362203 | 0.89 | CFTR (0.41) | LMNAHTTPOLBMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL8516825 | 0.89 | CA12 (0.40) | LMNAMAPTMEN1KMT2AUSP2 | |
| Trifluoroacetic Acid SCHEMBL8515708 | 0.87 | CFTR (0.46) | LMNAHTTPOLBNPM1BRD4 | |
| Trifluoroacetic Acid SCHEMBL8366749 | 0.85 | LMNA (0.41) | LMNAHTTPOLBMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL8367899 | 0.85 | LMNA (0.44) | LMNAHTTPOLBMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL8516484 | 0.84 | CFTR (0.45) | LMNAHTTPOLBNPM1BRD4 | |
| Trifluoroacetic Acid SCHEMBL8367897 | 0.83 | CFTR (0.40) | LMNAHTTPOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |