Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415572 | 1.00 | KIF11 (0.55) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28491862 | 0.91 | KIF11 (0.59) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15559247 | 0.91 | KIF11 (0.47) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28491134 | 0.84 | KIF11 (0.44) | KIF11KCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2328040 | 0.84 | KIF11 (0.52) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2326451 | 0.84 | KIF11 (0.52) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2327154 | 0.84 | KIF11 (0.52) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2328128 | 0.84 | KIF11 (0.52) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2324748 | 0.84 | KIF11 (0.52) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2326446 | 0.82 | KIF11 (0.53) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0890096-A1 | CATION-SELECTIVE SENSOR | INSTITUT FÜR CHEMO- UND BIOSENSORIK Münster e.V. (DE) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997037215-A1 | CATION-SELECTIVE SENSOR | Institut für Chemo- und Biosensorik Münster E.V. (DE) | 1997-10-09 | — | — | WO | disclosed |