Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 0.62 |
| ▸ | ESR1 | P03372 | 7/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178493 | 1.00 | ESR2 (0.62) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517074 | 0.95 | ESR2 (0.63) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517256 | 0.95 | ESR2 (0.57) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517248 | 0.95 | ESR2 (0.57) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517252 | 0.95 | ESR2 (0.57) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517075 | 0.95 | ESR2 (0.63) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517080 | 0.95 | ESR2 (0.63) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL11210601 | 0.91 | ESR2 (0.47) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL11210597 | 0.91 | ESR2 (0.47) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10935713 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4235939-A | — | — | None | — | — | JP | disclosed |
| JP-59172438-A | — | — | None | — | — | JP | disclosed |
| JP-58188841-A | — | — | None | — | — | JP | disclosed |
| JP-58188840-A | — | — | None | — | — | JP | disclosed |
| JP-58185579-A | — | — | None | — | — | JP | disclosed |
| JP-58210046-A | — | — | None | — | — | JP | disclosed |
| JP-58210047-A | — | — | None | — | — | JP | disclosed |
| JP-5058925-A | — | — | None | — | — | JP | disclosed |
| JP-58210045-A | — | — | None | — | — | JP | disclosed |
| JP-57054148-A | — | — | None | — | — | JP | disclosed |
| JP-S58210045-A | 4-ALPHA,ALPHA,ALPHA-TRIFLUOROMETHYLBENZOIC ACID 4-(TRANS-4'- ALKYLCYCLOHEXYL)PHENYL ESTER | CHISSO CORP | 1983-12-07 | — | — | JP | disclosed |
| JP-S58188840-A | PENTAFLUOROBENZOIC ACID TRANS-4-(TRANS-4'-ALKYL-CYCLOHEXYL) PHENYL ESTER | CHISSO CORP | 1983-11-04 | — | — | JP | disclosed |
| JP-S58188841-A | 3,4-DICHLOROBENZOIC ACID TRANS-4-(TRANS-4'-ALKYL-CYCLOHEXYL) PHENYL ESTER | CHISSO CORP | 1983-11-04 | — | — | JP | disclosed |
| JP-S58185579-A | LIQUID CRYSTAL ESTER COMPOUND | SEIKO EPSON CORP | 1983-10-29 | — | — | JP | disclosed |
| US-4405488-A | LOW VISCOSITY, HIGH TRANSPARENT POINT | CHISSO CORPORATION (JP) | 1983-09-20 | — | — | US | disclosed |
| JP-S5770839-A | TRANS-4-SUBSTITUTED CYCLOHEXANECARBOXYLIC ACID TRANS-4'-(TRANS-4\"-ALKYLCYCLOHEXYL) CYCLOHEXYL ESTER | CHISSO CORP | 1982-05-01 | — | — | JP | disclosed |
| JP-S5767539-A | TRANS-4'-(TRANS-4\"-ALKYLCYCLOHEXYL)-CYCLOHEXYL 3-HALOGENOBENZOATE | CHISSO CORP | 1982-04-24 | — | — | JP | disclosed |
| JP-S5754148-A | 4-HALOGENOBENZOIC ACID TRANS-4'(TRANS-4\"-ALKYLCYCLOHEXYL)CYCLOHEXYL ESTER | CHISSO CORP | 1982-03-31 | — | — | JP | disclosed |
| JP-S5732249-A | 3-HALOGENOBENZOIC ACID 4'-(TRANS-4\"-ALKYLCYCLOHEXYL)PHENYL ESTER | CHISSO CORP | 1982-02-20 | — | — | JP | disclosed |
| JP-S5731645-A | 4-HALOGENOBENZOIC ACID 4'-(TRANS-4\"-ALKYLCYCLOHEXYL)PHENYL ESTER | CHISSO CORP | 1982-02-20 | — | — | JP | disclosed |