Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 0.57 |
| ▸ | ESR1 | P03372 | 7/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517252 | 1.00 | ESR2 (0.57) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8517248 | 1.00 | ESR2 (0.57) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8516950 | 0.95 | ESR2 (0.62) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL178493 | 0.95 | ESR2 (0.62) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10935701 | 0.92 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10904852 | 0.92 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10935693 | 0.92 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10935713 | 0.92 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10904861 | 0.92 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10904854 | 0.92 | ESR2 (0.43) | ESR2ESR1CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59098038-A | — | — | None | — | — | JP | disclosed |
| JP-4103555-A | — | — | None | — | — | JP | disclosed |
| EP-0893424-A1 | ALPHA,ALPHA-DIFLUOROBENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| JP-H04103555-A | CYCLOBUTANE DERIVATIVE | CHISSO CORP | 1992-04-06 | — | — | JP | disclosed |
| US-4701547-A | POSITIVE DIELECTRIC ANISOTROPHY | CHISSO CORPORATION (JP) | 1987-10-20 | — | — | US | disclosed |
| EP-0099099-B1 | HIGH TEMPERATURE LIQUID CRYSTAL SUBSTANCES HAVING FOUR RINGS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | Chisso Corporation (JP) | 1987-04-08 | — | — | EP | disclosed |
| EP-0084974-B1 | CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES | Chisso Corporation (JP) | 1986-04-02 | — | — | EP | disclosed |
| EP-0090671-B1 | CARBOCYLIC ESTERS HAVING LIQUID-CRYSTAL PROPERTIES AT HIGH TEMPERATURES | Chisso Corporation (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4502974-A | SUBSTITUTED WITH HALOGEN OR NITRILE | CHISSO CORPORATION (JP) | 1985-03-05 | — | — | US | disclosed |
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4472293-A | High temperature liquid crystal substances of four rings and liquid crystal compositions containing the same | CHISSO CORPORATION (JP) | 1984-09-18 | — | — | US | disclosed |
| JP-S5998038-A | 2,4,5-TRIFLUOROBENZOIC ACID PHENYL ESTER | CHISSO CORP | 1984-06-06 | — | — | JP | disclosed |
| EP-0099099-A2 | High temperature liquid crystal substances having four rings and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1984-01-25 | — | — | EP | disclosed |
| EP-0090671-A1 | Carbocylic esters having liquid-crystal properties at high temperatures | Chisso Corporation (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0084974-A1 | Carbocyclic compounds with liquid-crystal properties | Chisso Corporation (JP) | 1983-08-03 | — | — | EP | disclosed |