SCHEMBL8517

SCHEMBL8517

c1ccc2c(c1)CCOO2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
ITGB2 P05107 1/20 0.40
ICAM1 P05362 1/20 0.40
ITGAL P20701 1/20 0.40
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.36
CRHBP P24387 2/20 0.36
CRHR2 Q13324 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.35
OXTR P30559 1/20 0.34
NISCH Q9Y2I1 1/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788643 1.00 MAOA (0.41) MAOAMAOBITGB2ICAM1ITGAL
SCHEMBL895328 1.00 MAOA (0.41) MAOAMAOBITGB2ICAM1ITGAL
SCHEMBL29788642 1.00 MAOA (0.41) MAOAMAOBITGB2ICAM1ITGAL
SCHEMBL107468 1.00 MAOA (0.41) MAOAMAOBITGB2ICAM1ITGAL
SCHEMBL11557711 0.98 MAOA (0.39) MAOAMAOBITGB2ICAM1ITGAL
Hydrochloric Acid SCHEMBL12503314 0.98 MAOA (0.39) MAOAMAOBITGB2ICAM1ITGAL
Methylamine SCHEMBL3886894 0.94 MAOA (0.37) MAOAMAOBITGB2ICAM1ITGAL
Bromomethane SCHEMBL3888146 0.94 MAOA (0.37) MAOAMAOBITGB2ICAM1ITGAL
Formaldehyde SCHEMBL28062094 0.94 MAOA (0.37) MAOAMAOBITGB2ICAM1ITGAL
Methyl Alcohol SCHEMBL3885098 0.94 CA12 (0.37) MAOAMAOBITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12826 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
CN-122036610-A Synthesis method of central chiral aza seven-membered bridged aromatic compound containing chiral axis 浙江大学 2026-05-15 CN claimed
US-12590100-B2 Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-β-TrCP interaction for use in the treatment of fatty liver disease UNIV MADRID AUTONOMA (ES) 2026-03-31 US claimed
US-20260069599-A1 INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 AND PHOSPHOINOSITIDE 3-KINASE UNIV NEBRASKA (US) 2026-03-12 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
WO-2025085347-A1 IL4I1 INHIBITORS AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-04-24 WO claimed
CN-119725417-A Composite positive electrode material, preparation method thereof, positive electrode plate, battery and power utilization device 宁德时代新能源科技股份有限公司 2025-03-28 CN claimed
US-12240844-B2 Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease VORONOI, INC. (KR) 2025-03-04 US claimed
CN-113557237-B Pyrrolopyridine derivatives and their use for preventing or treating protein kinase related diseases 沃若诺伊公司 2025-01-14 CN claimed
WO-2024251133-A1 HETEROCYCLIC COMPOUND AS α5-GABAA RECEPTOR MODULATOR AND USE THEREOF 武汉人福创新药物研发中心有限公司 2024-12-12 WO claimed
EP-0138280-A2 Blood-pressure lowering piperazine derivatives DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1985-04-24 EP claimed
EP-0038564-B1 DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM KYOWA HAKKO KOGYO CO., LTD (JP) 1984-09-12 EP claimed
EP-0042556-B1 PROCESS FOR THE MANUFACTURE OF ALKYLHYDRAZONE CATIONIC DYES AND THEIR DYESTUFF BASES BAYER AG (DE) 1984-02-08 EP claimed
EP-0095666-A2 Tetrahydro-benzo(e) isoindolines ABBOTT LABORATORIES (US) 1983-12-07 EP claimed
US-4376728-A Process for the preparation of cationic alkylarylhydrazone dyestuffs and color bases thereof BAYER AKTIENGESELLSCHAFT (DE) 1983-03-15 US claimed
EP-0004366-B1 HAIR DYEING COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1981-07-08 EP claimed
EP-0004435-B1 ETHERS OF 4-HALOMETHYLPYRIDINES, FUNGICIDAL COMPOSITIONS AND METHOD FOR PROTECTING PLANTS FROM FUNGAL DISEASE THE DOW CHEMICAL COMPANY (US) 1981-07-01 EP claimed
US-4217305-A HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1980-08-12 US claimed
US-4003746-A Organic heterocyclic and thioaryl phosphines in silver halide emulsions and developers therefor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-18 US claimed
US-3967835-A Pressure-sensitive copying material HODOGAYA CHEMICAL CO., LTD. (JA) 1976-07-06 US claimed