SCHEMBL8517037

SCHEMBL8517037

Cc1cccc(O)c1-c1c(O)ccc(S(=O)(=O)O)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
TRPA1 O75762 3/20 0.42
ATM Q13315 1/20 0.42
STAT3 P40763 1/20 0.39
NQO1 P15559 1/20 0.38
ELANE P08246 2/20 0.37
CTSG P08311 1/20 0.37
COMT P21964 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ESR1 P03372 1/20 0.36
GAA P10253 1/20 0.36
ESR2 Q92731 1/20 0.36
MAOA P21397 2/20 0.36
LDHA P00338 1/20 0.36
CDK2 P24941 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517228 0.88 NQO1 (0.41) AURKAAURKBNQO1COMTMEN1
SCHEMBL8516633 0.83 NQO1 (0.44) AURKAAURKBNQO1ELANECTSG
SCHEMBL8516702 0.83 ELANE (0.44) AURKAAURKBTRPA1ATMSTAT3
SCHEMBL8516483 0.83 NQO1 (0.44) AURKAAURKBTRPA1ATMSTAT3
Sulfamate SCHEMBL28288535 0.77 TRPA1 (0.45) AURKAAURKBTRPA1ATMMEN1
SCHEMBL7868085 0.77 STAT3 (0.50) AURKAAURKBTRPA1ATMSTAT3
SCHEMBL8516436 0.77 NQO1 (0.48) AURKAAURKBNQO1COMTMEN1
SCHEMBL34452 0.76 TRPA1 (0.48) AURKAAURKBTRPA1ATMSTAT3
SCHEMBL29881857 0.76 TRPA1 (0.48) AURKAAURKBTRPA1ATMSTAT3
SCHEMBL31521298 0.75 TRPA1 (0.62) TRPA1ATMELANECTSGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed