SCHEMBL8517102

SCHEMBL8517102

CS(=O)(=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
CXCR1 P25024 2/20 0.52
CXCR2 P25025 2/20 0.52
TAAR1 Q96RJ0 3/20 0.47
SLC6A2 P23975 1/20 0.47
LNPEP Q9UIQ6 3/20 0.47
ERAP2 Q6P179 2/20 0.47
YARS1 P54577 2/20 0.47
THRB P10828 1/20 0.46
MMP2 P08253 1/20 0.46
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17834728 0.86 CXCR1 (0.51) SLC7A5CXCR1CXCR2THRB
SCHEMBL16836845 0.86 ALPI (0.56) SLC7A5CXCR1CXCR2THRB
SCHEMBL16727787 0.86 ALPI (0.56) SLC7A5CXCR1CXCR2THRB
Hydrochloric Acid SCHEMBL17825443 0.85 CXCR1 (0.50) CXCR1CXCR2THRB
Hydrochloric Acid SCHEMBL17825499 0.85 CXCR1 (0.50) CXCR1CXCR2THRB
Tyrosine SCHEMBL17874441 0.81 SLC7A5 (0.80) SLC7A5TAAR1SLC6A2YARS1
Tyrosine SCHEMBL17874442 0.81 SLC7A5 (0.80) SLC7A5TAAR1SLC6A2YARS1
SCHEMBL30708085 0.80 SLC7A5 (0.62) SLC7A5TAAR1SLC6A2LNPEPERAP2
SCHEMBL2013830 0.80 SLC7A5 (0.62) SLC7A5TAAR1SLC6A2LNPEPERAP2
SCHEMBL2017291 0.80 SLC7A5 (0.62) SLC7A5TAAR1SLC6A2LNPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999052906-A1 SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO claimed
EP-3925627-A1 DRUG-CONJUGATES AND USES THEREOF Concortis Biosystems, Corp (US) 2021-12-22 EP disclosed
EP-3590541-B1 DRUG-CONJUGATES AND USES THEREOF CONCORTIS BIOSYSTEMS CORP (US) 2021-08-11 EP disclosed
US-20210187119-A1 Drug-Conjugates, Conjugation Methods, And Uses Thereof VIVASOR, INC. 2021-06-24 US disclosed
US-10967071-B2 Drug-conjugates, conjugation methods, and uses thereof CONCORTIS BIOSYSTEMS, CORP. (US) 2021-04-06 US disclosed
EP-3520817-A1 DRUG-CONJUGATES, CONJUGATION METHODS, AND USES THEREOF Concortis Biosystems, Corp (US) 2019-08-07 EP disclosed
EP-2849790-B1 DRUG-CONJUGATES, CONJUGATION METHODS, AND USES THEREOF CONCORTIS BIOSYSTEMS CORP (US) 2019-04-10 EP disclosed
US-9981046-B2 Drug-conjugates, conjugation methods, and uses thereof Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) 2018-05-29 US disclosed
US-20180085471-A1 DRUG-CONJUGATES, CONJUGATION METHODS, AND USES THEREOF SORRENTO THERAPEUTICS, INC. 2018-03-29 US disclosed
US-20180085471-A1 DRUG-CONJUGATES, CONJUGATION METHODS, AND USES THEREOF SORRENTO THERAPEUTICS, INC. 2018-03-29 US disclosed
US-9884127-B2 Drug-conjugates, conjugation methods, and uses thereof CONCORTIS BIOSYSTEMS, CORP. (US) 2018-02-06 US disclosed
US-9801951-B2 Drug-conjugates, conjugation methods, and uses thereof CONCORTIS BIOSYSTEMS, CORP. (US) 2017-10-31 US disclosed
US-9801951-B2 Drug-conjugates, conjugation methods, and uses thereof CONCORTIS BIOSYSTEMS, CORP. (US) 2017-10-31 US disclosed
US-20160067350-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) 2016-03-10 US disclosed
US-20150141646-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof Concortis Biosystems, Corp., a wholly owned subsidary of Sorrento Therapeutics, Inc, (US) 2015-05-21 US disclosed
US-20150141646-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof Concortis Biosystems, Corp., a wholly owned subsidary of Sorrento Therapeutics, Inc, (US) 2015-05-21 US disclosed
US-20150105539-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) 2015-04-16 US disclosed
US-20150105539-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180085471-A1 DRUG-CONJUGATES, CONJUGATION METHODS, AND USES THEREOF ABCG2, UGT2B7, UGT1A9 SLC7A5 73/4885CXCR1 2264/4885CXCR2 1760/4885
US-20160067350-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof PAICS, CES2, DNPEP SLC7A5 448/4885CXCR1 2387/4885CXCR2 1616/4885
US-20150141646-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof ABCG2, UGT2B7, UGT1A9 SLC7A5 73/4885CXCR1 2264/4885CXCR2 1760/4885
US-20210187119-A1 Drug-Conjugates, Conjugation Methods, And Uses Thereof PAICS, CES2, DNPEP SLC7A5 448/4885CXCR1 2387/4885CXCR2 1616/4885
US-10967071-B2 Drug-conjugates, conjugation methods, and uses thereof PAICS, CES2, DNPEP SLC7A5 448/4885CXCR1 2387/4885CXCR2 1616/4885
US-20150105539-A1 Drug-Conjugates, Conjugation Methods, and Uses Thereof PAICS, CES2, DNPEP SLC7A5 448/4885CXCR1 2387/4885CXCR2 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.