Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516815 | 0.94 | TSHR (0.51) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL8544946 | 0.87 | NAAA (0.55) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL8547287 | 0.82 | TDP1 (0.43) | TSHRNPSR1MAPTHPGDTDP1 | |
| SCHEMBL28263168 | 0.81 | TSHR (0.59) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL16040083 | 0.81 | TSHR (0.51) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL2280208 | 0.80 | TSHR (0.54) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL7567844 | 0.80 | TSHR (0.50) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL4000332 | 0.80 | TSHR (0.54) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL3688622 | 0.80 | TSHR (0.53) | TSHRNAAANPSR1MAPTMAPK1 | |
| SCHEMBL222069 | 0.79 | TSHR (0.52) | TSHRNAAANPSR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661310-B1 | Cyclo-olefincopolymers and process for their preparation | TICONA GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| EP-0661308-B1 | Cyclo-olefin copolymers and process for their preparation | TICONA GMBH (DE) | 1999-06-02 | — | — | EP | disclosed |
| US-5756623-A | MOLDING MATERIALS FOR COMPRESSION MOLDING | HOECHST AG (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0661310-A2 | Cyclo-olefincopolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661308-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |