Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8365272 | 0.92 | BRD4 (0.40) | BRD4ALDH1A1LMNAHTTHIF1A | |
| Trifluoroacetic Acid SCHEMBL4687029 | 0.91 | BRD4 (0.51) | BRD4CNR1GHSRHRH1CCNT1 | |
| Trifluoroacetic Acid SCHEMBL8516225 | 0.90 | BRD4 (0.39) | BRD4ALDH1A1LMNAHTTHIF1A | |
| SCHEMBL8538027 | 0.85 | BRD4 (0.56) | BRD4GHSRHRH1CCNT1CDK7 | |
| Trifluoroacetic Acid SCHEMBL8516220 | 0.84 | BRD4 (0.47) | BRD4ALDH1A1LMNAHIF1ACNR1 | |
| Trifluoroacetic Acid SCHEMBL8516597 | 0.82 | BRD4 (0.44) | BRD4LMNAHTTCNR1HRH1 | |
| Trifluoroacetic Acid SCHEMBL8516085 | 0.82 | KMT2A (0.40) | ALDH1A1LMNAHIF1ANPSR1PTGDR2 | |
| SCHEMBL8517321 | 0.82 | BRD4 (0.42) | BRD4ALDH1A1LMNAHTTHIF1A | |
| Trifluoroacetic Acid SCHEMBL8368507 | 0.81 | BRD4 (0.43) | BRD4GHSRACP1CCNT1CDK7 | |
| Trifluoroacetic Acid SCHEMBL8365238 | 0.81 | MAPT (0.44) | KMT2AMEN1USP2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |