Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312459 | 1.00 | USP30 (0.39) | USP30CCR2ESR2DGAT1SOAT1 | |
| SCHEMBL4931479 | 0.91 | USP30 (0.38) | USP30CCR2ESR2USP5HDAC6 | |
| SCHEMBL4931475 | 0.91 | USP30 (0.38) | USP30CCR2ESR2USP5HDAC6 | |
| SCHEMBL8517594 | 0.87 | OPRL1 (0.36) | ESR2DGAT1CYP2C9OPRL1 | |
| SCHEMBL9313677 | 0.87 | OPRL1 (0.36) | ESR2DGAT1CYP2C9OPRL1 | |
| SCHEMBL2272516 | 0.86 | USP5 (0.37) | USP30CCR2ESR2USP5HDAC6 | |
| SCHEMBL2272518 | 0.86 | USP5 (0.37) | USP30CCR2ESR2USP5HDAC6 | |
| SCHEMBL8451674 | 0.86 | USP5 (0.37) | USP30CCR2ESR2USP5HDAC6 | |
| SCHEMBL2272522 | 0.86 | USP5 (0.37) | USP30CCR2ESR2USP5HDAC6 | |
| SCHEMBL8517389 | 0.85 | ESR2 (0.36) | USP30CCR2ESR2DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |