Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.36 |
| ▸ | PTGIR | P43119 | 3/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517594 | 1.00 | OPRL1 (0.36) | OPRL1PTGIRPTGDRESR2DGAT1 | |
| SCHEMBL8972154 | 0.92 | SLC6A2 (0.35) | PTGIRPTGDRESR2HSD11B1PANK3 | |
| SCHEMBL9311759 | 0.92 | SLC6A2 (0.35) | PTGIRPTGDRESR2HSD11B1PANK3 | |
| SCHEMBL8517272 | 0.87 | SLC6A2 (0.40) | ESR2DGAT1CYP2C9 | |
| SCHEMBL9312527 | 0.87 | SLC6A2 (0.40) | ESR2DGAT1CYP2C9 | |
| SCHEMBL8517432 | 0.87 | USP30 (0.39) | OPRL1ESR2DGAT1CYP2C9 | |
| SCHEMBL9312459 | 0.87 | USP30 (0.39) | OPRL1ESR2DGAT1CYP2C9 | |
| SCHEMBL8518707 | 0.86 | OPRL1 (0.36) | OPRL1ESR2HSD11B1 | |
| SCHEMBL8518711 | 0.86 | OPRL1 (0.36) | OPRL1ESR2HSD11B1 | |
| SCHEMBL8518709 | 0.86 | OPRL1 (0.36) | OPRL1ESR2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |