SCHEMBL8517523

SCHEMBL8517523

C=CCOC(=O)C(F)(F)S(=O)(=O)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
TSHR P16473 2/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502010 0.86 ALDH1A1 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL28270705 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8207148 0.77 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL1082749 0.77 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL11444238 0.75 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
Ammonia Solution, Strong SCHEMBL11233126 0.75 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL28761387 0.75 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL28427366 0.75 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL29506833 0.75 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL758493 0.74 ALDH1A1 (0.39) TSHRMAPTALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11246590-A None JP disclosed
CN-106973990-B fumigation method for preventing and controlling entomophthora in grains 中国科学院上海有机化学研究所 2019-12-10 CN disclosed
CN-106973901-B It is a kind of for preventing and treating the fumigating method of historical relic entomophthora 中国科学院上海有机化学研究所 2019-11-12 CN disclosed
JP-H11246590-A PRODUCTION OF TRIFLUOROMETHYLURACIL DERIVATIVE ASAHI GLASS CO LTD 1999-09-14 JP disclosed