Pyrogallol

Pyrogallol

SCHEMBL8517613

Nc1cccc2cccc(N)c12.Oc1cccc(O)c1O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
CDK2 P24941 3/20 0.55
ALOX15 P16050 3/20 0.55
HPGD P15428 3/20 0.55
HSD17B10 Q99714 3/20 0.55
RECQL P46063 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MMP2 P08253 2/20 0.55
ADAMTS4 O75173 1/20 0.55
EGFR P00533 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
LMNA P02545 1/20 0.55
FYN P06241 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
CA6 P23280 1/20 0.55
MMP12 P39900 1/20 0.55
ADAMTS5 Q9UNA0 1/20 0.55
TSHR P16473 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechol SCHEMBL8517030 0.88 ALOX15 (0.56) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL29365168 0.86 TSHR (0.52) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL30845313 0.86 TSHR (0.52) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL444774 0.86 TSHR (0.52) ALDH1A1CDK2ALOX15HPGDHSD17B10
Lithium SCHEMBL29431813 0.84 TSHR (0.50) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL7916033 0.84 TSHR (0.50) ALDH1A1CDK2ALOX15HPGDHSD17B10
Hydrochloric Acid SCHEMBL31157040 0.84 TSHR (0.50) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL31511770 0.84 TSHR (0.50) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL7916031 0.84 TSHR (0.50) ALDH1A1CDK2ALOX15HPGDHSD17B10
SCHEMBL29349435 0.83 JAK2 (0.54) ALDH1A1ALOX15HPGDHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1063460-C Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 2001-03-21 CN disclosed
US-5889103-A CONSISTS OF A POLYMER OF QUINONE OR DERIVATIVES, A WATER SOLUBLE POLYMER, AN INORGANIC COLLOID AND AN ALKALI METAL SILICATE; USED AS ANTISCALING AGENT IN POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS IN ALKALINE SOLUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-30 US disclosed
EP-0760378-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1999-01-27 EP disclosed
CN-1039334-C Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1998-07-29 CN disclosed
US-5728781-A POLYMERIZING AN UNSATURATED MONOMER IN A VESSEL HAVING A COATING FILM ON THE INNER WALL SURFACE THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-17 US disclosed
EP-0632058-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-01-28 EP disclosed
US-5691428-A Process for producing a polymer using a quinone compound condensation product polymer scale preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-11-25 US disclosed
EP-0760378-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0540934-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1997-02-05 EP disclosed
EP-0534434-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1996-12-11 EP disclosed
US-5457170-A Coating interior wall of vessel used for addition polymerization SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-10-10 US disclosed
US-5442017-A Addition polymerization in vessel with interior wall coating comprised of condesation product of aromatic amine, aromatic alcohol and acetone plus polymeric material and colloidal silica SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-08-15 US disclosed
US-5424003-A Preventive coatings for equipment and reactors used for addition polymerization of unsaturated compounds; antideposit agents; amino resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-06-13 US disclosed
US-5399613-A Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-03-21 US disclosed
CN-1097768-A Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1995-01-25 CN disclosed
EP-0632058-A1 Polymer scale preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-01-04 EP disclosed
CN-1074685-A The medicament of preventing polymer fouling, container and application SHINETSU CHEMICAL CO (JP) 1993-07-28 CN disclosed
EP-0540934-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-05-12 EP disclosed
EP-0534434-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-31 EP disclosed