Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243414 | 0.95 | HTT (0.47) | HTTKMT2AHSD17B10ESR1HIF1A | |
| SCHEMBL8861929 | 0.89 | PARP10 (0.44) | HTTKMT2AHSD17B10ESR1HIF1A | |
| SCHEMBL8518197 | 0.86 | HTT (0.58) | HTTKMT2AHSD17B10ESR1HIF1A | |
| Hydrochloric Acid SCHEMBL8517634 | 0.84 | HTT (0.57) | HTTHSD17B10ELANEALDH1A1L3MBTL1 | |
| SCHEMBL9283080 | 0.82 | ESR2 (0.41) | HTTKMT2AHSD17B10ESR1ELANE | |
| SCHEMBL19764523 | 0.82 | THRB (0.50) | HTTKMT2AHSD17B10ESR1HIF1A | |
| SCHEMBL9346190 | 0.82 | HTT (0.42) | HTTKMT2AHSD17B10ESR1HIF1A | |
| SCHEMBL740811 | 0.80 | THRB (0.47) | KMT2AHSD17B10SMN1; SMN2ELANEALDH1A1 | |
| SCHEMBL8770703 | 0.80 | HTT (0.63) | HTTKMT2AHSD17B10ESR1HIF1A | |
| Hydrochloric Acid SCHEMBL9243417 | 0.79 | HTT (0.61) | HTTKMT2AHSD17B10ESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891359-A | FLUOROTRIESTERAROMATIC COMPOUND FOR LIQUID CRYSTALS | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0571277-B1 | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5320776-A | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1994-06-14 | — | — | US | disclosed |
| EP-0571277-A1 | Antiferroelectric liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1993-11-24 | — | — | EP | disclosed |