SCHEMBL8517643

SCHEMBL8517643

CC(C)(c1ccccc1)c1ccc(C(C)(C)c2ccccc2)c(-c2cccc(S(=O)(=O)O)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.47
CNR2 P34972 3/20 0.47
NR3C2 P08235 3/20 0.40
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
TSHR P16473 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
NR1H3 Q13133 1/20 0.36
PTPN1 P18031 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BRD4 O60885 1/20 0.34
C1S P09871 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517641 0.90 CNR1 (0.44) CNR1CNR2NR3C2ESR1ESR2
SCHEMBL7422495 0.82 TSHR (0.52) CNR1CNR2NR3C2ESR1ESR2
SCHEMBL8608504 0.80 TSHR (0.50) CNR1CNR2NR3C2ESR1ESR2
SCHEMBL21726601 0.77 ALDH1A1 (0.52) NR3C2ESR1ESR2TSHRSMN1; SMN2
SCHEMBL8516981 0.76 NR3C2 (0.48) CNR1CNR2NR3C2ESR1ESR2
SCHEMBL7738073 0.74 NR3C2 (0.62) NR3C2ESR1ESR2TSHRSMN1; SMN2
SCHEMBL5305260 0.72 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL8365847 0.72 CNR1 (0.38) CNR1CNR2NR3C2ESR1ESR2
SCHEMBL9766543 0.72 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL28360131 0.72 TSHR (0.43) TSHRSMN1; SMN2ALDH1A1PTPN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed